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Natural Products/Bioactive Compounds as a Source of Anticancer Drugs

Fatih Ramazan İSTANBULLUGİL

Simple Summary Cancer is considered as a large group of diseases involving abnormal cell growth, which results in an alarming rise in the mortality rate at the worldwide level. Presently, the main point of interest in pharmaceutical research is the development of the novel and efficient anticancer drugs based on natural sources. In this regard, plants, and some microbial species, due to their composition, ecology, phytochemical, and ethnopharmacological properties, play a significant role. Accordingly, a series of plant-derived bioactive compounds are in the clinical development phase against ...Более

Обзор 2022 Veteriner Fakültesi Cansers24 ( 24 ) 28 Просмотры
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The Utilization of Bee Products as a Holistic Approach to Managing Polycystic Ovarian Syndrome-Related Infertility

Ulaş ACARÖZ

Bee products, including honey, have been utilized since ancient times for nutritional and therapeutic purposes. Recently, other bee products such as bee pollen, royal jelly, and propolis have caught a lot of attention. Being high in antioxidants and bioactive compounds, these products have established their applications in the pharmaceutical field as supplementary or alternative medicines. This review focuses on their use against polycystic ovarian syndrome (PCOS)-related infertility. A systematic search of electronic databases including PubMed, Web of Science ScienceDirect, and Google Scholar ...Более

Обзор 2023 Veteriner Fakültesi Nutrients15 ( 5 ) 61 Просмотры
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The power of retrotransposons in high-throughput genotyping and sequencing

Yılmaz KAYA

The use of molecular markers has become an essential part of molecular genetics through their application in numerous fields, which includes identification of genes associated with targeted traits, operation of backcrossing programs, modern plant breeding, genetic characterization, and marker-assisted selection. Transposable elements are a core component of all eukaryotic genomes, making them suitable as molecular markers. Most of the large plant genomes consist primarily of transposable elements; variations in their abundance contribute to most of the variation in genome size. Retrotransposon ...Более

Обзор 2023 Fen Fakültesi Frontiers in Plant Science14 51 Просмотры
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Review on Propolis Applications in Food Preservation and Active Packaging

Ulaş ACARÖZ | Damla ARSLAN ACARÖZ

Propolis is a natural hive product collected by honeybees from different plants and trees. The collected resins are then mixed with bee wax and secretions. Propolis has a long history of use in traditional and alternative medicine. Propolis possesses recognized antimicrobial and antioxidant properties. Both properties are characteristics of food preservatives. Moreover, most propolis components, in particular flavonoids and phenolic acids, are natural constituents of food. Several studies suggest that propolis could find use as a natural food preservative. This review is focused on the potenti ...Более

Обзор 2023 Veteriner Fakültesi Plants12 ( 8 ) 29 Просмотры
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Production of secondary metabolites using tissue culture-based biotechnological applications

Yılmaz KAYA

Plants are the sources of many bioactive secondary metabolites which are present in plant organs including leaves, stems, roots, and flowers. Although they provide advantages to the plants in many cases, they are not necessary for metabolisms related to growth, development, and reproduction. They are specific to plant species and are precursor substances, which can be modified for generations of various compounds in different plant species. Secondary metabolites are used in many industries, including dye, food processing and cosmetic industries, and in agricultural control as well as being use ...Более

Обзор 2023 Fen Fakültesi Frontiers in Plant Science14 17 Просмотры
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Mechanisms of probiotic Bacillus against enteric bacterial infections

Damla ARSLAN ACARÖZ | Fatih Ramazan İSTANBULLUGİL | Ulaş ACARÖZ

Gastrointestinal infection is a leading cause of gut diseases attracting global health concerns. The emerging antimicrobial resistance in enteric pathogens drives the search of viable and renewable alternatives to antibiotics for the health of both human beings and animals. Spore-forming probiotic Bacillus have received extensively interests for their multiple health benefits, including the restoration of microbiota dysbiosis and the reduction of drug-resistant pathogens. These promising benefits are mainly attributed to the activity of structurally diverse Bacillus-derived metabolites, such a ...Более

Обзор 2023 Veteriner Fakültesi One Health Advances ( 1 ) 14 Просмотры
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Sepsis-induced cardiomyopathy in animals: From experimental studies to echocardiography-based clinical research

İsmail ŞEN

The term sepsis-induced cardiomyopathy (SIC) is used to describe transient cardiac dysfunction in septic patients. However, there is no universally accepted definition of SIC; a reduction in left ventricular ejection fraction (LVEF) is often used. In addition to systolic dysfunction, diastolic dysfunction is now recognized as an essential component of SIC. It can be emphasized that previous animal experiments played an essential role in revealing SIC and hemodynamic instability in sepsis and septic shock. The diagnostic and prognostic capabilities of echocardiography for the assessment of SIC ...Более

Обзор 2023 Veteriner Fakültesi Canadian Veterinary Journal64 ( 9 ) 11 Просмотры
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The Role of Bee Products in the Control of Antimicrobial Resistance and Biofilm Formation

Ulaş ACARÖZ | Fatih Ramazan İSTANBULLUGİL | Damla ARSLAN ACARÖZ

The discovery of antibiotics saved many lives. Infections were not as deadly a problem for clinicians as they once were. However, due to inappropriate and excessive use of antibiotics, antibiotic resistance has increased dramatically worldwide. Infectious diseases are becoming more challenging to control, and they cause increased morbidity and mortality. Also, a significant risk to human health is posed by infections associated with biofilms. To combat these drug-resistant microorganisms, several novel and alternative strategies have been identified. Bee products such as honey, bee pollen, pro ...Более

Обзор 2024 Veteriner Fakültesi Kafkas Üniversitesi Veteriner Fakültesi Dergisi30 ( 2 ) 3 Просмотры
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Molecular imprinted polymers: important advances in biochemistry, biomedical and biotechnology

Kalıypa SALİYEVA | Bakıt BORKOYEV

Molecularly imprinted polymers (MIPs) are handmade receptors that mimic the binding of natural antibodies. In other words, MIPs can selectively bind to the target molecule and qualify as bio-inspired synthetic materials. Today, MIPs are used extensively and are being developed further for biological applications. High cost and time consuming techniques are compelling factors for the field of biochemistry, biomedicine and biotechnology (3B), and there is an urgent need for an alternative, cheap, easy to produce, fast and effective method in these fields. MIPs stand out as a promising way for th ...Более

Обзор 2024 Mühendislik Fakültesi Polymer Bulletin ( Published online: 27 March 2024 ) 22 Просмотры
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Cotton Biotechnology: An Efficient Gene Transfer Protocol via Agrobacterium tumefaciens for a Greater Transgenic Recovery

İbrahim İlker ÖZYİĞİT | Yılmaz KAYA

Due to its economic worth, cotton (Gossypium hirsutum L.) is grown in almost 70 countries and provides income for more than 250 million people. Therefore, producing cotton with having some desired characteristics that includes extended biotic and abiotic stress tolerance, improved fiber quality, promoted nutritional content and increased yield is the main objective for cotton biotechnology. To achieve this goal, many tissue culture and gene transfer techniques are being developed and used throughout the years. As applications for the gene transfer, the Agrobacterium-mediated, particle bombardm ...Более

Обзор 2022 Fen Fakültesi Journal of Natural Fibers19 ( 15 ) 115 Просмотры
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Cotton Agriculture in Turkey and Worldwide Economic Impacts of Turkish Cotton

İbrahim İlker ÖZYİĞİT

Cotton is a product that provides wealth for humanity with its widespread and compulsory usage, and alongside creating employment opportunities in the producer countries. Due to the availability of suitable land for agriculture, seven countries including Turkey produce close to 80% of cotton worldwide. The average cotton yield in Turkey is above the world average, placing the country close to first place among the major producing countries. On the other hand, Turkey is one of the main countries engaged in organic cotton production by using only non-transgenic seeds and therefore, its cotton as ...Более

Обзор 2022 Fen Fakültesi Journal of Natural Fibers19 ( 15 ) 147 Просмотры
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Future research avenues at the nexus of circular economy and digitalization

Serhat BURMAOĞLU

Purpose The authors posit that one of the key enablers of the circular economy will be the digital transformation - in other words, digitalization. In this study, the authors examine and visualize the interaction of the circular economy and digitalization by using scientific publications. They explore possible synergies and future research avenues at this junction. Design/methodology/approach The authors first apply bibliometrics to explore and visualize the relationships between the circular economy and digitalization in the academic literature. Following the clustering of topics, they define ...Более

Обзор 2022 İktisadi ve İdari Bilimler Fakültesi International Journal of Productivity and Performance Management72 ( 8 ) 94 Просмотры
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