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Найденный: 4 Экземпляр 0.001 sn
Кафедра : Kimya Mühendisliği B ... ✕Тематический рубрикатор : paracetamol ✕
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Determination of Acetaminophen in Commercial Formulations Using Silver Nanostructured Aniline Modified Pencil Graphite Electrode

Ali Osman SOLAK

A nanostructured silver-aniline modified pencil electrode obtained by applying experimental design and optimization was developed for the differential pulse stripping voltammetric quantification of acetaminophen in the pharmaceutical products, tablet and syrup. The electrode development process was performed by the modification of PGE with aniline using CV procedure and the reduction of silver nanoparticle on the polyaniline modified PGE. As a result, a new electrode system consisting of a nanostructured silver-polyaniline modified pencil graphite electrode (AgNS-PA-PGE) was obtained to reach ...Более

Статья 2013 Mühendislik Fakültesi Journal of The Electrochemical Society160 ( 8 ) 73 Просмотры
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Agar and Sesame Oil Based Organo-Hydrogels as a Pharmaceutical Excipient in Paracetamol/Carboplatin Release Systems

Nahit AKTAŞ

Organo-hydrogels were synthesized by using free radical polymerization in the emulsion technique, using agar, glycerol, sesame oil, ammonium persulfate as initiator and N,N'-methylene bisacrylamide or glutaraldehyde as crosslinker. Swelling behaviors, blood compatibility, antioxidant and properties of the organo-hydrogels were investigated thoroughly. The highest swelling value was seen in organo-hydrogel synthesized with the N,N'-methylene bisacrylamide crosslinker containing 0.1 ml of sesame oil. Moreover, drug release behaviors of organo-hydrogels were studied as paracetamol and carboplatin ...Более

Статья 2022 Mühendislik Fakültesi Indian Journal of Pharmaceutical Sciences84 ( 2 ) 41 Просмотры
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New Voltammetric Approach to the Quantitation of Paracetamol in Tablets and Syrup using Chemometric Optimization Technique

Ali Osman SOLAK

A new voltammetric approach was developed for the determination of paracetamol in tablet and syrup samples using chemometric optimization. The method is based on the use of the gold nanoparticles-polyaniline (AuNPs-PA) modified pencil graphite electrode (PGE). Electrode system was fabricated by using the electrochemical reduction of gold on aniline modified pencil electrode to give gold nanoparticles. A 3(3) full factorial design was used to find optimal oxidation conditions of paracetamol on the AuNPs-PA-PGE. The optimal oxidation conditions of drug substance were found as -524 mV for the acc ...Более

Статья 2019 Mühendislik Fakültesi Journal of Analytical Chemistry74 ( 3 ) 51 Просмотры
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Synthesis and characterization of novel organo-hydrogel based agar, glycerol and peppermint oil as a natural drug carrier/release material

Nahit AKTAŞ

The very recent Covid-19 pandemic has made the need to understand biocompatible polymers as support material in drug delivery systems and controlled release clearer, especially for organo-hydrogels. This study aims to synthesize various new polymeric materials called gels, hydrogels, and organo-hydrogels according to the monomer used and to investigate their use as drug release systems. The agar-glycerol (AG) pair was used to synthesize the polymers, N, N, methylene bisacrylamide (MBA, m) and glutaraldehyde (GA, g) were used as cross-linkers and peppermint oil (PmO) was included to obtain the ...Более

Статья 2021 Mühendislik Fakültesi Materials Science and Engineering: C - Materials For Biological Applications118 107 Просмотры
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