Exposure assessment of dairy cows to parabens using hair samples analysis

Parabens (PBs) are used as preservatives in various products. They pollute the environment and penetrate living organisms, showing endocrine disrupting activity. Till now studies on long-term exposure of farm animals to PBs have not been performed. Among matrices using in PBs biomonitoring hair samples are becoming more and more important. During this study concentration levels of methyl paraben (MeP), ethyl paraben (EtP), propyl paraben (PrP) butyl paraben (BuP) and benzyl paraben (BeP) were evaluated using liquid chromatography-mass spectrometry (LC-MS) in hair samples collected from dairy cows bred in the Kyrgyz Republic. MeP was noted in 93.8 of samples (with mean concentration levels 62.2 ± 61.8 pg/mg), PrP in 16.7 of samples (12.4 ± 6.5 pg/mg) and EtP in 8.3 of samples (21.4 ± 11.9 pg/mg). BuP was found only in one sample (2.1) and BeP was not detected in any sample included in the study. Some differences in MeP concentration levels in the hair samples depending on district, where cows were bred were noted. This study has shown that among PBs, dairy cows are exposed mainly to MeP, and hair samples may be a suitable matrix for research on PBs levels in farm animals.

Keyword: biomonitoring; Central Asia; farm animals; LC–MS method; methyl paraben (MeP)