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Предметтик рубрикатор : oxidative stress ✕

Коллекция [2]

Окумуштуулар [6]

БУУнун туруктуу өнүгүүсү [7]

Факультет / Институт [2]

Басылманын түрү [1]

Жарыяланган жылы [7]

Тили [1]

Булагы [10]

Маалымат базалар [8]

Индекс түрү [3]

Басмаканасы [8]

Бөлүмү [2]

Улуттук/Эл аралык [1]

Предметтик рубрикатор [56]

Hepatoprotective potentials of Usnea longissima Ach. and Xanthoparmelia somloensis (Gyelnik) Hale extracts in ethanol-induced liver injury

Ali ASLAN

In our study, the antioxidant and anti-inflammatory effects of different lichen applications were investigated in rats using an experimental ethanol toxicity model. 48 rats were used in the study and they were divided into 6 groups with 8 rats in each group. These groups were: control, ethanol (2 g/kg), ethanol Usnea longissima Ach. (200 mg/kg), ethanol Usnea longissima Ach. (400 mg/kg), ethanol Xanthoparmelia somloensis (Gyelnik) Hale (100 mg/kg) and ethanol Xanthoparmelia somloensis (Gyelnik) Hale (200 mg/kg). The experimental work continued for 21 days. Lichen extracts and ethanol were admi ...Дагы

Макала 2024 Fen Fakültesi Drug and Chemical Toxicology ( Published online: 25 Sep 2024 ) 1 Көрүүлөр

Physiological and biochemical effects of nickel on rainbow trout (Oncorhynchus mykiss) tissues: Assessment of nuclear factor kappa B activation, oxidative stress and histopathological changes

Ertan ORUC

We investigated changes in nuclear factor kappa B (NFkB) activity, antioxidant responses and histopathological effects in the liver, gill and kidney tissues of rainbow trout exposed to nickel chloride (Ni). Two different concentrations (1 mg/L and 2 mg/L) were administrated to fish for 21 days. Tissues were taken from all fish for NFkB activity, histopathological examination and determination of superoxide dismutase (SOD), catalase (CAT) enzyme activity and of lipid peroxidation (LPO), and glutathione (GSH) levels. The findings of this study indicated that Ni exposure led to a significant incr ...Дагы

Макала 2017 Veteriner Fakültesi Chemosphere166 107 Көрүүлөр

Cytogenetic and Oxidative Status of Cultured Lymphocytes after Exposure to Extracts from Rhizopogon Mushrooms (Agaricomycetes) In Vitro

Ali ASLAN

In this study, acetone and water extracts obtained from edible mushrooms, Rhizopogon luteolus Fr. and Rh. roseolus (Corda) Th. Fr., containing important bioactive components were used. Total antioxidant capacity (TAC) and total oxidative stress (TOS) levels were examined on human peripheral lymphocyte culture treated with the respective extracts. Levels of genetic damage and cytotoxic effects of the respective extracts on lymphocytes were also tested. In general, when TAC levels of the extracts on cells were examined, a concentration-dependent increase was observed; a negative correlation was ...Дагы

Макала 2021 Fen Fakültesi International Journal of Medicinal Mushrooms23 ( 3 ) 102 Көрүүлөр

Prophylactic effect of myricetin and apigenin against lipopolysaccharide-induced acute liver injury

Ali ASLAN

Background Liver has an important role in the initiation and progression of multiple organ failure that occurs in sepsis. Many natural active substances can be used to reduce the liver injury caused by sepsis. For this aim, the effects of myricetin and apigenin on mice model of acute liver injury was evaluated in this study. Methods and results Thirty-six mice were randomly divided into six groups as; control, lipopolysaccharide (LPS) (5 mg/kg), LPS myricetin (100 mg/kg), LPS myricetin (200 mg/kg), LPS apigenin (100 mg/kg), and LPS apigenin (200 mg/kg) groups. Myricetin and apigenin were admin ...Дагы

Макала 2021 Fen Fakültesi Molecular Biology Reports48 ( 9 ) 47 Көрүүлөр

THE PHYSIOLOGICAL AND DNA DAMAGE RESPONSE OF IN THE LICHEN HYPOGYMNIA PHYSODES TO UV AND HEAVY METAL STRESS

Ali ASLAN

This work aims to determine the response of Hypogymnia physodes (L.) Nyl. (hooded tube lichen) collected in an unpolluted site (Yenice Forest in Karabiik, Turkey) to stress conditions. In the present study, the effect of exposure to different heavy metals (Cd 2, Pb 2, and Cr 6) for different durations and UV radiations dosages on lichen was examined at the physiological and molecular levels. The effects of stress conditions were determined in the case of different parameters concerning heavy metal, protein, chlorophyll, and carotenoid contents and changes in the DNA profiles. According to the ...Дагы

Макала 2020 Fen Fakültesi Applied Ecology and Environmental Research18 ( 2 ) 37 Көрүүлөр

Abiotic stress-induced regulation of antioxidant genes in different Arabidopsis ecotypes: microarray data evaluation

İbrahim İlker ÖZYİĞİT

Although stresses induce generation of reactive oxygen species (ROS), which are highly reactive and toxic, and cause severe damage to cellular components; plants have very efficient enzymatic ROS-scavenging mechanisms. Despite the substantial knowledge produced about these enzymes, we still have limited knowledge regarding their expression patterns in relation to the stress type, duration and strength. Thus, taking advantage of microarray data, this work evaluated the abiotic stresses (salt, cold, heat and light) induced regulation of six antioxidant enzymes, superoxide dismutase (SOD), catala ...Дагы

Макала 2019 Fen Fakültesi Biotechnology and Biotechnological Equipment33 ( 1 ) 100 Көрүүлөр

Reducing oxidative stress by kappa-carrageenan and C60HyFn: The post-thaw quality and antioxidant status of Azari water buffalo bull semen

Damla ARSLAN ACARÖZ

Azeri water buffalo is a species of great interest due to the high quality of its products such as milk. Due to the decreasing trend of its number and risk of extinction in the future, our attention is directed towards ensuring the preservation of its genetic reserves by keeping its sperm. Using antioxidants in semen extender is one of the ways to reduce the detrimental effects of freezing process on post-thawed quality of spermatozoa. This study was conducted to determine the effect of κ-carrageenan (k-CRG) and C60HyFn supplemented semen extender on the quality of post-thawed Azari water buff ...Дагы

Макала 2023 Veteriner Fakültesi Cryobiology111 31 Көрүүлөр

Investigation of antiepileptic potentials of usnic acid and some lichen species on the behavioral and biochemical levels in pentylenetetrazole-induced kindling model of epilepsy

Ali ASLAN

In this study, the effects of various lichen and usnic acid applications on seizure scores and biochemical parameters in brain tissue in rats with epilepsy model was investigated. For this aim, 91 rats were divided into 13 groups, each containing 7 rats, which were: control, pentylenetetrazole (PTZ) (35 mg/kg), PTZ Valproic acid (100 mg/kg), PTZ Dolichousnea longissima (200 mg/kg), PTZ Dolichousnea longissima (400 mg/kg), PTZ Xanthoparmelia somloensis (50 mg/kg), PTZ Xanthoparmelia somloensis (200 mg/kg), PTZ Cetraria islandica (250 mg/kg), PTZ Cetraria islandica (500 mg/kg), PTZ Pseudevernia ...Дагы

Макала 2024 Fen Fakültesi Journal of Research in Pharmacy28 ( 5 ) 14 Көрүүлөр

Magnolin alleviates cyclophosphamide-induced oxidative stress, inflammation, and apoptosis via Nrf2/HO-1 signaling pathway

Damla ARSLAN ACARÖZ | Ulaş ACARÖZ

In the present study, we investigated the protective effect of magnolin (MAG) against oxidative stress induced by cyclophosphamide (CP) and its role in the Nrf2/HO-1 signaling pathway. Rats were administered MAG (1 mg/kg, i.p.) for 14 days and CP (75 mg/kg, i.p.) on the 14th day. CP administration increased tissue damage, as evidenced by elevated levels of transaminases (aspartate and alanine), alkaline phosphatase, and renal parameters (blood urea nitrogen and creatinine). Additionally, 8-hydroxy-2́-deoxyguanosine and malondialdehyde levels were increased, whereas glutathione levels, along wi ...Дагы

Макала 2024 Veteriner Fakültesi Toxicology Research13 ( 4 ) 6 Көрүүлөр

The Effect of Chlorpyrifos on isolated Thoracic Aorta in Rats

Oğuz KUL

This study investigated the effect of chlorpyrifos on thoracic aorta and on the level of NO in plasma and aorta. The effect of chlorpyrifos on thoracic aorta in organ bath was determined in 10 rats. Another 45 rats were assigned to 3 groups with 15 rats each: control group 1 received distilled water, control group 2 was given corn oil, and the last group was given 13.5 mg/kg chlorpyrifos dissolved in corn oil every other day for 8 weeks orally. Chlorpyrifos (10−10 M–10−5 M) showed no effect on isolated thoracic aorta. Plasma AChE activity was decreased, while LDH, ALT, GGT, and AST activities ...Дагы

Макала 2013 Veteriner Fakültesi BioMed Research International376051 76 Көрүүлөр