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Prof. Dr. Nahit AKTAŞMühendislik Fakültesi
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A novel carbohydrate antigen 125 electrochemical sensor based on sweet almond oil organo-hydrogels

Nahit AKTAŞ

Ovarian cancer is a gynecological disease causing many deaths among women around the world. Carbohydrate antigen 125 (CA-125) is a single biomarker known to be a tumor marker of ovarian cancer. CA-125 is widely used to monitor the treatment process, recurrences, and for the detection of ovarian cancer. Herein, organo-hydrogels were prepared in order to detect CA-125 sensitively in serum medium with electrochemical methods. Organo-hydrogels were obtained by the free radical polymerization reaction using agar and glycerol with varying proportions of sweet almond oil using methylene bisacrylamide ...More

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Novel Cacao oil-based organo-hydrogels to detect carcinoma antigen 125 in serum medium; synthesis, characterization, and electrochemical measurements

Nahit AKTAŞ

In present study, cacao oil-based organo-hydrogels (OHCOs) are synthesized to detect carcinoma antigen 125 (CA-125) in serum medium with electrochemical methods such as cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). OHCOs are prepared by the free radical polymerization reaction with agar, glycerol, and distinct ratios of cacao oil with glutaraldehyde (GA) crosslinker or methylene bisacrylamide (MBA) crosslinker. OHCOs are characterized via Fourier Transform Infrared Spec-troscopy (FT-IR), in different solvent environments and pH ...More

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