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Bu çalışmanın amacı, medetomidin/ketamin (MED-KET) ve ksilazin/ketamin (KSZ-KET) anestezisindeki kedilerde kısa süreli kardiyovasküler etkilerini ve atipamezol ile bu etkilerinin geri dönüşümünü ekokardiyografi tekniği ile araştırmaktı. Erişkin 20 dişi kedi (ağırlığı 2.2-3.6 kg ve yaşı 0.5-5.5 arasında) ovariyohisterektomi için getirildi. Elektrokardiyogram, invaziv olmayan kan basıncı ölçümü, solunum sayısı, kalp atımı ve periferik oksijen düzeyi anestezi süresince izlendi. Her iki grup anestezi indüksiyonundan sonra sol ventrikül çapı (LVD) ve sol ventrikül fırlatma fraksiyonu (EF) azalması ...More
The neonatal heart is different from the adult heart in regard to both biochemical and structural features. Echocardiographic studies in human neonatology show that the myocardial function of left ventricle (LV) of premature infants differs from term infants. No study involving myocardial performance index (MPI) in neonatal animals has been performed until now. The objective of the present study was to evaluate LV MPI in premature calves and compare it to healthy newborn term calves. Ten healthy term and 20 premature calves were used. Echocardiographic evaluations were performed at days 1, 2, ...More
The reaction of the cardiovascular system to anesthetics can be various and different, based on dosing, the experimental model, and agent sele-ction. A few studies have compared the effects of different anesthetic agents used for trans-thoracic echocardiography on cardiac functions in dogs; however, none of these studies examined the effects of different anesthetic regimes and their reversal by atipamezole echoc ardio graph icall y. The aim of this study was to investigate, visualize, and clarify in vivo both the short-term echocardiographic impacts of medet omidi ne-ke tamin e and medet omidi ...More
Degenerative mitral valve disease (DMVD) is the leading cause of cardiac disease and heart failure in the dog. Advanced age, breed and male gender are well-known risk factors for DMVD. The incidence of the disease in German Shepherds seems to be noteworthy. Early diagnosis of DMVD is related to the identification of a left apical systolic murmur, characteristic of MR in a dog. Dogs with DMVD had a low frequency of arrhythmias compared to other cardiac conditions. The goal of the study was (i) to evaluate the age and gender incidences of the asymptomatic Anatolian Shepherd Dogs (ASHs) with DMVD ...More
The goal of this study was to determine the distribution of left ventricular (LV) systolic and diastolic dysfunctions and their prognostic value in canine parvovirus-infected dogs suffering from severe sepsis and septic shock (SS/SS). Twenty dogs with SS/SS (experimental group) and 18 healthy dogs (control group) were used in the study. Systolic and diastolic dysfunction was present in three (15%) and 14 (70%) diseased dogs, respectively, with both types of dysfunction present in two (10%) of the patients. These dogs were split into two groups: survivors (Sv, n = 14) and non-survivors (non-Sv, ...More
This study was performed to evaluate the end systolic wall stress/end-systolic volume index ratio (ESWS/ESV-I) for LV systolic function in Anatolian shepherd dogs (ASHs) with stage B2 degenerative mitral valve disease (DMVD). Thirty-eight adult ASHs with DMVD (experimental group; 20 B1 dogs and 18 B2 dogs) and 30 weight-matched adult healthy ASHs (control group) were used as subjects. There was no overlap for the ESW5/ESV-I ratio (0.83 +/- 0.03, range: 0.61-1.09 for B2 dogs, 1.34 +/- 0.05, range: 1.11-1.89 for B1 dogs, 2.171 +/- 0.0 range: 1.91-3.02 for the control dogs) among the groups. ESWS ...More
Echocardiographic studies in human neonatology has demonstrated that prematurity can lead to cardiovascular dysfunction and especially compromises the left ventricular (LV) systolic and diastolic functions. As echocardiographic studies have not been performed on cardiovascular dysfunction in premature calves, we echocardiographically evaluated and compared the LV systolic and diastolic function in full-term and premature calves. We followed the hemodynamical changes of LV during first 3 days of life. Twenty premature calves and 10 healthy term calves were enrolled in the study. 2D, M-mode and ...More