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Fatih Ramazan İSTANBULLUGİL | Ali RIŞVANLI | Ruslan SALIKOV | Nariste KADIRALİYEVA | Ayday CUNUŞOVA
Immune compatibility between mare and foal is one of the important topics of reproductive immunology. At this point, although there are many studies on antibodies, there are not many publications on the relationship between the cytokine levels of mare, foal and milk and the effects of milk composition on this relationship. Here we investigate the relationship between Th1/Th2 cytokine balance and milk composition in Kyrgyz mares and foals. Samples were taken soon after the foal was born and on days 5, 10 and 20 after birth. Th1 (IFN-γ, IL-2, TNF-α) and Th2 (IL-4, IL-5, IL-10) cytokine levels in ...More
Damla ARSLAN ACARÖZ | Fatih Ramazan İSTANBULLUGİL | Ulaş ACARÖZ
Gastrointestinal infection is a leading cause of gut diseases attracting global health concerns. The emerging antimicrobial resistance in enteric pathogens drives the search of viable and renewable alternatives to antibiotics for the health of both human beings and animals. Spore-forming probiotic Bacillus have received extensively interests for their multiple health benefits, including the restoration of microbiota dysbiosis and the reduction of drug-resistant pathogens. These promising benefits are mainly attributed to the activity of structurally diverse Bacillus-derived metabolites, such a ...More
Fatih Ramazan İSTANBULLUGİL | Ulaş ACARÖZ | Damla ARSLAN ACARÖZ
Foodborne pathogens like Salmonella and Listeria monocytogenes are microbial agents capable of causing severe illnesses, and they pose a perpetual menace to the food industry. Given their potential to jeopardize human health, both food producers and consumers hold significant concerns regarding these pathogens. The quest for novel strategies and natural preservatives in the domain of food safety holds paramount importance in the effort to curtail the dissemination and contamination of these pathogens. In this context, honey stands out as a notable natural product with substantial potential. Ho ...More
Fatih Ramazan İSTANBULLUGİL | Ali RIŞVANLI | Ruslan SALIKOV | Ulaş ACARÖZ | Damla ARSLAN ACARÖZ
The aim of the present study was to determine the relationship of immunoglobulins and cytokine levels in the milk of Kyrgyz mares during the last period of lactation. For this purpose, seven Kyrgyz mares were used. During the last week of lactation, milk samples were obtained from mares four times at intervals of two days. Physicochemical tests were performed on all collected milk samples, and pH, fat, ash, titratable acidity, and dry matter were measured. Interferon-gamma (IFN-γ), interleukin-2 (IL-2), tumour necrosis factor-alpha (TNF-α), and immunoglobulin G (IgG) levels were determined usi ...More
Ulaş ACARÖZ | Fatih Ramazan İSTANBULLUGİL | Damla ARSLAN ACARÖZ
The discovery of antibiotics saved many lives. Infections were not as deadly a problem for clinicians as they once were. However, due to inappropriate and excessive use of antibiotics, antibiotic resistance has increased dramatically worldwide. Infectious diseases are becoming more challenging to control, and they cause increased morbidity and mortality. Also, a significant risk to human health is posed by infections associated with biofilms. To combat these drug-resistant microorganisms, several novel and alternative strategies have been identified. Bee products such as honey, bee pollen, pro ...More
Honey is a natural food that has been used since ancient times for its medicinal benefits. Thanks to its antimicrobial activity, which has a very important place among honey's medicinal effects, it can be used against various pathogens such as Staphylococcus aureus and Escherichia coli. The antibacterial effect of honey depends on physical (high osmotic pressure, low water activity and low pH value), chemical (hydrogen peroxide, methylglyocal, phenolic compounds, flavonoids, organic acids and proteins) and biological factors (enzymes secreted by bees, probiotic bacteria and pollen). The antiba ...More
Fatih Ramazan İSTANBULLUGİL | Hüseyin KARADAĞ | Şamil SEFERGİL
The purpose of this study was to investigate the formation of the plexus sacralis in the Kyrgyz pheasant (Phasianus colchicus mongolicus) and the origin of the nerves emerging from the plexus sacralis. Five adult male Kyrgyz pheasants were used that had been hunted in their natural habitat near the town of Tokmok in the Chuy region of Kyrgyzstan. The plexus sacralis was found to be formed in the lumbar region by the ventral strands of sacral nerves 1 to 5, originating in the spinal cord. The plexus is composed of the truncus cranialis, which consists of the ventral strands of the first 3 nerve ...More
Hüseyin KARADAĞ | Fatih Ramazan İSTANBULLUGİL | Şamil SEFERGİL
Bu çalışma, Beyaz Hindide Arteria (a) celiaca ve dallarının orijini ve seyrini tespit amacı ile yapıldı. Çalışmada kullanılan 5 adet ergin dişi beyaz hindi Van-Et Ticari Yatırımlar Gıda Sanayi Turizm İç ve Dış Ticaret A.Ş’den temin edildi. Premedikasyon ve sedasyon amacı ile İ.M xylazine-ketamin uygulaması yapıldıktan sonra, pıhtılaşmayı önlemek için Vena (v) axillaris’ten heparin verildi. Derin anasteziden sonra, thoracoabdominal boşluk açıldı ve aorta abdominalis kesilerek hayvanın kanı akıtıldı. Aynı yolla kumaş boyası ile renklendirilmiş latex enjekte edildikten sonra kadavralar %10 formal ...More
Bee products have been extensively employed in traditional therapeutic practices to treat several diseases and microbial infections. Numerous bioactive components of bee products have exhibited several antibacterial, antifungal, antiviral, anticancer, antiprotozoal, hepatoprotective, and immunomodulatory properties. Apitherapy is a form of alternative medicine that uses the bioactive properties of bee products to prevent and/or treat different diseases. This review aims to provide an elaborated vision of the antiviral activities of bee products with recent advances in research. Since ancient t ...More
Microbial biofilm is an aggregation of microbial species that are either attached to surfaces or organized into an extracellular matrix. Microbes in the form of biofilms are highly resistant to several antimicrobials compared to planktonic microbial cells. Their resistance developing ability is one of the major root causes of antibiotic resistance in health sectors. Therefore, effective antibiofilm compounds are required to treat biofilm-associated health issues. The awareness of biofilm properties, formation, and resistance mechanisms facilitate researchers to design and develop combating str ...More
Simple Summary Cancer is considered as a large group of diseases involving abnormal cell growth, which results in an alarming rise in the mortality rate at the worldwide level. Presently, the main point of interest in pharmaceutical research is the development of the novel and efficient anticancer drugs based on natural sources. In this regard, plants, and some microbial species, due to their composition, ecology, phytochemical, and ethnopharmacological properties, play a significant role. Accordingly, a series of plant-derived bioactive compounds are in the clinical development phase against ...More
Gıda güvenliği, artık günümüz dünyasında uluslararası bir mesele olarak algılanmakta ve ülkeler gıda güvenliğinin sağlanması için gerekli önlemleri almak amacıyla yoğun gayret göstermektedirler. Gıda güvenliğinin sağlanmasında ise bireylerin gıda güvenliği bilinç düzeyi önemli bir rol oynamaktadır. Bu çalışmada Bişkek ilinde öğrenim gören üniversite öğrencilerinin gıda güvenliği konusunda bilinçli düzeylerinin araştırılması amaçlanmıştır. Çalışma için 12 üniversiteden 83 Kız 80 Erkek öğrenci ile yüz yüze anket yapılmıştır. Araştırmada, katılımcıların önemli bir kesiminin gıda güvenliği kavramı ...More