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Databases : Web of Science Core ... ✕Researcher : Fatih Ramazan İSTANB ... ✕
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Yrd. Doç. Dr. Fatih Ramazan İSTANBULLUGİLVeteriner Fakültesi
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The relationship between Th1/Th2 cytokine polarization and milk composition in the postnatal period in Kyrgyz mares and foals

Fatih Ramazan İSTANBULLUGİL | Ali RIŞVANLI | Ruslan SALIKOV | Nariste KADIRALİYEVA | Ayday CUNUŞOVA

Immune compatibility between mare and foal is one of the important topics of reproductive immunology. At this point, although there are many studies on antibodies, there are not many publications on the relationship between the cytokine levels of mare, foal and milk and the effects of milk composition on this relationship. Here we investigate the relationship between Th1/Th2 cytokine balance and milk composition in Kyrgyz mares and foals. Samples were taken soon after the foal was born and on days 5, 10 and 20 after birth. Th1 (IFN-γ, IL-2, TNF-α) and Th2 (IL-4, IL-5, IL-10) cytokine levels in ...More

Article 2023 Veteriner Fakültesi Reproduction in Domestic Animals58 ( 6 ) 22 Views
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The relationship between milk components, immunoglobulins, and cytokine content at the end of lactation in Kyrgyz mares

Fatih Ramazan İSTANBULLUGİL | Ali RIŞVANLI | Ruslan SALIKOV | Ulaş ACARÖZ | Damla ARSLAN ACARÖZ

The aim of the present study was to determine the relationship of immunoglobulins and cytokine levels in the milk of Kyrgyz mares during the last period of lactation. For this purpose, seven Kyrgyz mares were used. During the last week of lactation, milk samples were obtained from mares four times at intervals of two days. Physicochemical tests were performed on all collected milk samples, and pH, fat, ash, titratable acidity, and dry matter were measured. Interferon-gamma (IFN-γ), interleukin-2 (IL-2), tumour necrosis factor-alpha (TNF-α), and immunoglobulin G (IgG) levels were determined usi ...More

Article 2023 Veteriner Fakültesi South African Journal of Animal Science53 ( 6 ) 3 Views
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The Role of Bee Products in the Control of Antimicrobial Resistance and Biofilm Formation

Ulaş ACARÖZ | Fatih Ramazan İSTANBULLUGİL | Damla ARSLAN ACARÖZ

The discovery of antibiotics saved many lives. Infections were not as deadly a problem for clinicians as they once were. However, due to inappropriate and excessive use of antibiotics, antibiotic resistance has increased dramatically worldwide. Infectious diseases are becoming more challenging to control, and they cause increased morbidity and mortality. Also, a significant risk to human health is posed by infections associated with biofilms. To combat these drug-resistant microorganisms, several novel and alternative strategies have been identified. Bee products such as honey, bee pollen, pro ...More

Review 2024 Veteriner Fakültesi Kafkas Üniversitesi Veteriner Fakültesi Dergisi30 ( 2 ) 3 Views
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Formation of the plexus sacralis in pheasants (Phasianus colchicus mongolicus) and macroanatomic investigation of the nerves originating from the plexus sacralis

Fatih Ramazan İSTANBULLUGİL | Hüseyin KARADAĞ | Şamil SEFERGİL

The purpose of this study was to investigate the formation of the plexus sacralis in the Kyrgyz pheasant (Phasianus colchicus mongolicus) and the origin of the nerves emerging from the plexus sacralis. Five adult male Kyrgyz pheasants were used that had been hunted in their natural habitat near the town of Tokmok in the Chuy region of Kyrgyzstan. The plexus sacralis was found to be formed in the lumbar region by the ventral strands of sacral nerves 1 to 5, originating in the spinal cord. The plexus is composed of the truncus cranialis, which consists of the ventral strands of the first 3 nerve ...More

Article 2013 Veteriner Fakültesi Turkish Journal of Veterinary and Animal Sciences37 ( 2 ) 58 Views
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General Nutritional Profile of Bee Products and Their Potential Antiviral Properties against Mammalian Viruses

Fatih Ramazan İSTANBULLUGİL

Bee products have been extensively employed in traditional therapeutic practices to treat several diseases and microbial infections. Numerous bioactive components of bee products have exhibited several antibacterial, antifungal, antiviral, anticancer, antiprotozoal, hepatoprotective, and immunomodulatory properties. Apitherapy is a form of alternative medicine that uses the bioactive properties of bee products to prevent and/or treat different diseases. This review aims to provide an elaborated vision of the antiviral activities of bee products with recent advances in research. Since ancient t ...More

Review 2022 Veteriner Fakültesi Nutrients14 ( 17 ) 30 Views
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Natural Strategies as Potential Weapons against Bacterial Biofilms

Fatih Ramazan İSTANBULLUGİL

Microbial biofilm is an aggregation of microbial species that are either attached to surfaces or organized into an extracellular matrix. Microbes in the form of biofilms are highly resistant to several antimicrobials compared to planktonic microbial cells. Their resistance developing ability is one of the major root causes of antibiotic resistance in health sectors. Therefore, effective antibiofilm compounds are required to treat biofilm-associated health issues. The awareness of biofilm properties, formation, and resistance mechanisms facilitate researchers to design and develop combating str ...More

Review 2022 Veteriner Fakültesi Life-Basel12 ( 10 ) 65 Views
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Natural Products/Bioactive Compounds as a Source of Anticancer Drugs

Fatih Ramazan İSTANBULLUGİL

Simple Summary Cancer is considered as a large group of diseases involving abnormal cell growth, which results in an alarming rise in the mortality rate at the worldwide level. Presently, the main point of interest in pharmaceutical research is the development of the novel and efficient anticancer drugs based on natural sources. In this regard, plants, and some microbial species, due to their composition, ecology, phytochemical, and ethnopharmacological properties, play a significant role. Accordingly, a series of plant-derived bioactive compounds are in the clinical development phase against ...More

Review 2022 Veteriner Fakültesi Cansers24 ( 24 ) 28 Views
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Determination of AFM(1) Levels of Mare's Milk and Koumiss Produced in the Highlands of the Kyrgyz Republic

Fatih Ramazan İSTANBULLUGİL

Mare's milk and koumiss are two very important basic foodstuffs in central Asia.This study aimed to research the AFM(1) contamination in mare's milk and koumiss samples collected from local producers in the highlands in Naryn, Issyk-Kul, Bishkek and Talas regions of Kyrgyz Republic. For this purpose, 75 raw mare's milk and 75 koumiss samples collected in May, June and July 2017 were analyzed using the ELISA method. ARM was detected in 13.3% of the 75 raw mare's milk samples with levels ranging between 6.48 and 25.45 ng/L. Approximately 53.3% of the koumiss samples were found to contain AFM(1), ...More

Article 2021 Veteriner Fakültesi Kafkas Üniversitesi Veteriner Fakültesi Dergisi27 ( 1 ) 115 Views
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