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A novel carbohydrate antigen 125 electrochemical sensor based on sweet almond oil organo-hydrogels

Nahit AKTAŞ

Ovarian cancer is a gynecological disease causing many deaths among women around the world. Carbohydrate antigen 125 (CA-125) is a single biomarker known to be a tumor marker of ovarian cancer. CA-125 is widely used to monitor the treatment process, recurrences, and for the detection of ovarian cancer. Herein, organo-hydrogels were prepared in order to detect CA-125 sensitively in serum medium with electrochemical methods. Organo-hydrogels were obtained by the free radical polymerization reaction using agar and glycerol with varying proportions of sweet almond oil using methylene bisacrylamide ...More

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Metrisor: A novel diagnostic method for metritis detection in cattle based on machine learning and sensors

Ali RIŞVANLI

The Metrisor device has been developed using gas sensors for rapid, highly accurate and effective diagnosis of metritis. 513 cattle uteri were collected from abattoirs and swabs were taken for microbiological testing. The Metrisor device was used to measure intrauterine gases. The results showed a bacterial growth rate of 75.75 in uteri with clinical metritis. In uteri positive for clinical metritis, the most commonly isolated and identified bacteria were Trueperella pyogenes, Fusobacterium necrophorum and Escherichia coli. Measurements taken with Metrisor to determine the presence of metritis ...More

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Novel gallium-based voltammetric sensor for sensitive detection of cysteine

Nahit AKTAŞ

Carbon nanotube-supported gallium (Ga/CNT) was synthesized and characterized with energy dispersive X-ray scanning electron microscopy, temperature-programmed reduction, temperature-programmed oxidation, and temperature-programmed desorption methods. Characterization results revealed successful preparation of Ga/ CNT. Electrochemical measurements were performed by cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. The Ga/CNT-based cysteine sensor had a linear response within the range of 0-200 mu M with current sensitivity of 0.0081 mu A/mu M (114 m ...More

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Novel Cacao oil-based organo-hydrogels to detect carcinoma antigen 125 in serum medium; synthesis, characterization, and electrochemical measurements

Nahit AKTAŞ

In present study, cacao oil-based organo-hydrogels (OHCOs) are synthesized to detect carcinoma antigen 125 (CA-125) in serum medium with electrochemical methods such as cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). OHCOs are prepared by the free radical polymerization reaction with agar, glycerol, and distinct ratios of cacao oil with glutaraldehyde (GA) crosslinker or methylene bisacrylamide (MBA) crosslinker. OHCOs are characterized via Fourier Transform Infrared Spec-troscopy (FT-IR), in different solvent environments and pH ...More

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Novel 5-(2-phenylbenzo [b] thiophen-3-yl)furan-2-carbaldehyde based ovarian cancer carbohydrate antigen 125 electrochemical sensor

Hilal DEMİR KIVRAK

Herein, an electrochemical sensor based 5-(2-phenylbenzo [b] thiophen-3-yl)furan-2-carbaldehyde (PTFC) was developed for the detection of cancer antigen 125 (CA125). Measurements were obtained via cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV), and square wave voltammetry (SWV) techniques to investigate features of the electrochemical sensor such as concentration effect of CA125, incubation time, scan rate, limit of quantification (LOQ), limit of detection (LOD), and interference effect of structures found in serum. The sensor wa ...More

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