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Publisher : Indian Pharmaceutica ... ✕Department : Kimya Mühendisliği B ... ✕
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Agar and Sesame Oil Based Organo-Hydrogels as a Pharmaceutical Excipient in Paracetamol/Carboplatin Release Systems

Nahit AKTAŞ

Organo-hydrogels were synthesized by using free radical polymerization in the emulsion technique, using agar, glycerol, sesame oil, ammonium persulfate as initiator and N,N'-methylene bisacrylamide or glutaraldehyde as crosslinker. Swelling behaviors, blood compatibility, antioxidant and properties of the organo-hydrogels were investigated thoroughly. The highest swelling value was seen in organo-hydrogel synthesized with the N,N'-methylene bisacrylamide crosslinker containing 0.1 ml of sesame oil. Moreover, drug release behaviors of organo-hydrogels were studied as paracetamol and carboplatin ...More

Article 2022 Mühendislik Fakültesi Indian Journal of Pharmaceutical Sciences84 ( 2 ) 41 Views
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