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The Utilization of Bee Products as a Holistic Approach to Managing Polycystic Ovarian Syndrome-Related Infertility

Ulaş ACARÖZ

Bee products, including honey, have been utilized since ancient times for nutritional and therapeutic purposes. Recently, other bee products such as bee pollen, royal jelly, and propolis have caught a lot of attention. Being high in antioxidants and bioactive compounds, these products have established their applications in the pharmaceutical field as supplementary or alternative medicines. This review focuses on their use against polycystic ovarian syndrome (PCOS)-related infertility. A systematic search of electronic databases including PubMed, Web of Science ScienceDirect, and Google Scholar ...More

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The power of retrotransposons in high-throughput genotyping and sequencing

Yılmaz KAYA

The use of molecular markers has become an essential part of molecular genetics through their application in numerous fields, which includes identification of genes associated with targeted traits, operation of backcrossing programs, modern plant breeding, genetic characterization, and marker-assisted selection. Transposable elements are a core component of all eukaryotic genomes, making them suitable as molecular markers. Most of the large plant genomes consist primarily of transposable elements; variations in their abundance contribute to most of the variation in genome size. Retrotransposon ...More

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Review on Propolis Applications in Food Preservation and Active Packaging

Ulaş ACARÖZ | Damla ARSLAN ACARÖZ

Propolis is a natural hive product collected by honeybees from different plants and trees. The collected resins are then mixed with bee wax and secretions. Propolis has a long history of use in traditional and alternative medicine. Propolis possesses recognized antimicrobial and antioxidant properties. Both properties are characteristics of food preservatives. Moreover, most propolis components, in particular flavonoids and phenolic acids, are natural constituents of food. Several studies suggest that propolis could find use as a natural food preservative. This review is focused on the potenti ...More

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Production of secondary metabolites using tissue culture-based biotechnological applications

Yılmaz KAYA

Plants are the sources of many bioactive secondary metabolites which are present in plant organs including leaves, stems, roots, and flowers. Although they provide advantages to the plants in many cases, they are not necessary for metabolisms related to growth, development, and reproduction. They are specific to plant species and are precursor substances, which can be modified for generations of various compounds in different plant species. Secondary metabolites are used in many industries, including dye, food processing and cosmetic industries, and in agricultural control as well as being use ...More

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Sepsis-induced cardiomyopathy in animals: From experimental studies to echocardiography-based clinical research

İsmail ŞEN

The term sepsis-induced cardiomyopathy (SIC) is used to describe transient cardiac dysfunction in septic patients. However, there is no universally accepted definition of SIC; a reduction in left ventricular ejection fraction (LVEF) is often used. In addition to systolic dysfunction, diastolic dysfunction is now recognized as an essential component of SIC. It can be emphasized that previous animal experiments played an essential role in revealing SIC and hemodynamic instability in sepsis and septic shock. The diagnostic and prognostic capabilities of echocardiography for the assessment of SIC ...More

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The Role of Bee Products in the Control of Antimicrobial Resistance and Biofilm Formation

Ulaş ACARÖZ | Fatih Ramazan İSTANBULLUGİL | Damla ARSLAN ACARÖZ

The discovery of antibiotics saved many lives. Infections were not as deadly a problem for clinicians as they once were. However, due to inappropriate and excessive use of antibiotics, antibiotic resistance has increased dramatically worldwide. Infectious diseases are becoming more challenging to control, and they cause increased morbidity and mortality. Also, a significant risk to human health is posed by infections associated with biofilms. To combat these drug-resistant microorganisms, several novel and alternative strategies have been identified. Bee products such as honey, bee pollen, pro ...More

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Cotton Biotechnology: An Efficient Gene Transfer Protocol via Agrobacterium tumefaciens for a Greater Transgenic Recovery

İbrahim İlker ÖZYİĞİT | Yılmaz KAYA

Due to its economic worth, cotton (Gossypium hirsutum L.) is grown in almost 70 countries and provides income for more than 250 million people. Therefore, producing cotton with having some desired characteristics that includes extended biotic and abiotic stress tolerance, improved fiber quality, promoted nutritional content and increased yield is the main objective for cotton biotechnology. To achieve this goal, many tissue culture and gene transfer techniques are being developed and used throughout the years. As applications for the gene transfer, the Agrobacterium-mediated, particle bombardm ...More

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Cotton Agriculture in Turkey and Worldwide Economic Impacts of Turkish Cotton

İbrahim İlker ÖZYİĞİT

Cotton is a product that provides wealth for humanity with its widespread and compulsory usage, and alongside creating employment opportunities in the producer countries. Due to the availability of suitable land for agriculture, seven countries including Turkey produce close to 80% of cotton worldwide. The average cotton yield in Turkey is above the world average, placing the country close to first place among the major producing countries. On the other hand, Turkey is one of the main countries engaged in organic cotton production by using only non-transgenic seeds and therefore, its cotton as ...More

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Future research avenues at the nexus of circular economy and digitalization

Serhat BURMAOĞLU

Purpose The authors posit that one of the key enablers of the circular economy will be the digital transformation - in other words, digitalization. In this study, the authors examine and visualize the interaction of the circular economy and digitalization by using scientific publications. They explore possible synergies and future research avenues at this junction. Design/methodology/approach The authors first apply bibliometrics to explore and visualize the relationships between the circular economy and digitalization in the academic literature. Following the clustering of topics, they define ...More

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Polymeric Organo-Hydrogels: Novel Biomaterials for Medical, Pharmaceutical, and Drug Delivery Platforms

Nahit AKTAŞ

In the recent two decades, tremendous devices and materials such as stents, biomimetic organs, scaffolds, and vessels have been developed for medical purposes. When such devices are utilized in the body, the side effects or biocompatibility of the materials have to be studied extensively. Interdisciplinary studies have reviled numerous strategies to overcome adverse body reactions against implanted devices. Besides naturally occurring materials such as collagen, chitosan, hyaluronic acid, and dextran, various synthetic and modified materials such as poly(lactic acid), poly(ethylene glycol), po ...More

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General Nutritional Profile of Bee Products and Their Potential Antiviral Properties against Mammalian Viruses

Fatih Ramazan İSTANBULLUGİL

Bee products have been extensively employed in traditional therapeutic practices to treat several diseases and microbial infections. Numerous bioactive components of bee products have exhibited several antibacterial, antifungal, antiviral, anticancer, antiprotozoal, hepatoprotective, and immunomodulatory properties. Apitherapy is a form of alternative medicine that uses the bioactive properties of bee products to prevent and/or treat different diseases. This review aims to provide an elaborated vision of the antiviral activities of bee products with recent advances in research. Since ancient t ...More

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Natural Strategies as Potential Weapons against Bacterial Biofilms

Fatih Ramazan İSTANBULLUGİL

Microbial biofilm is an aggregation of microbial species that are either attached to surfaces or organized into an extracellular matrix. Microbes in the form of biofilms are highly resistant to several antimicrobials compared to planktonic microbial cells. Their resistance developing ability is one of the major root causes of antibiotic resistance in health sectors. Therefore, effective antibiofilm compounds are required to treat biofilm-associated health issues. The awareness of biofilm properties, formation, and resistance mechanisms facilitate researchers to design and develop combating str ...More

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