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Novel Cacao oil-based organo-hydrogels to detect carcinoma antigen 125 in serum medium; synthesis, characterization, and electrochemical measurements

Nahit AKTAŞ

In present study, cacao oil-based organo-hydrogels (OHCOs) are synthesized to detect carcinoma antigen 125 (CA-125) in serum medium with electrochemical methods such as cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). OHCOs are prepared by the free radical polymerization reaction with agar, glycerol, and distinct ratios of cacao oil with glutaraldehyde (GA) crosslinker or methylene bisacrylamide (MBA) crosslinker. OHCOs are characterized via Fourier Transform Infrared Spec-troscopy (FT-IR), in different solvent environments and pH ...More

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Novel 5-(2-phenylbenzo [b] thiophen-3-yl)furan-2-carbaldehyde based ovarian cancer carbohydrate antigen 125 electrochemical sensor

Hilal DEMİR KIVRAK

Herein, an electrochemical sensor based 5-(2-phenylbenzo [b] thiophen-3-yl)furan-2-carbaldehyde (PTFC) was developed for the detection of cancer antigen 125 (CA125). Measurements were obtained via cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV), and square wave voltammetry (SWV) techniques to investigate features of the electrochemical sensor such as concentration effect of CA125, incubation time, scan rate, limit of quantification (LOQ), limit of detection (LOD), and interference effect of structures found in serum. The sensor wa ...More

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