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Тематический рубрикатор : 5-fluorouracil ✕Ученые : Nahit AKTAŞ ✕
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Prof. Dr. Nahit AKTAŞMühendislik Fakültesi
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Use of Coconut Oil-Based Organo-Hydrogels in Pharmaceutical Applications

Nahit AKTAŞ

In this study, six different organo-hydrogel containing Agar-Glycerol (AG) based Coconut Oil (CnO) were synthesized using different crosslinkers to ensure the controlled release of D-3 Vitamine and 5-Fluorouracil (5-Flu). Synthesized organo-hydrogels were characterized by FT-IR, Afterwards, swelling behaviors were investigated in ethanol, acetone, ethanol/ID water (1:1), acetone /ID water (1:1) and gasoline environments and different pH. As a result of hemolysis, blood clotting and antioxidant analysis, organo-hydrogels have been shown to have blood compatibility and antioxidant properties. Th ...Более

Статья 2021 Mühendislik Fakültesi Journal of Polymers and the Environment30 ( 2 ) 127 Просмотры
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Developing poly(Agar-co-Glycerol-co-Thyme Oil) based organo-hydrogels for the controlled drug release applications

Nahit AKTAŞ

In this study, it was aimed to investigate the synthesis, characterization and drug release behaviors of organohydrogels containing pH-sensitive Agar (A), Glycerol (G), Thyme Oil (TO). The novel organo-hydrogels containing TO were prepared in an emulsion media by the free-radical polymerization and crosslinking reactions among Agar (A), Glycerol (G), TO, N, N, methylenebisacrylamide (MBA) or glutaraldehyde (GA) reagent. Swelling ability (ethanol, acetone, ethanol/ID water (1:1), acetone/ID water (1:1) and gasoline environments and different pH), Fourier Transform Infrared Spectroscopy (FTIR) a ...Более

Статья 2020 Mühendislik Fakültesi Journal of Drug Delivery Science and Technology60 138 Просмотры
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