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Факультет / Институт : Fen Fakültesi ✕Тематический рубрикатор : oxidative stress ✕
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Abiotic stress-induced regulation of antioxidant genes in different Arabidopsis ecotypes: microarray data evaluation

İbrahim İlker ÖZYİĞİT

Although stresses induce generation of reactive oxygen species (ROS), which are highly reactive and toxic, and cause severe damage to cellular components; plants have very efficient enzymatic ROS-scavenging mechanisms. Despite the substantial knowledge produced about these enzymes, we still have limited knowledge regarding their expression patterns in relation to the stress type, duration and strength. Thus, taking advantage of microarray data, this work evaluated the abiotic stresses (salt, cold, heat and light) induced regulation of six antioxidant enzymes, superoxide dismutase (SOD), catala ...Более

Статья 2019 Fen Fakültesi Biotechnology and Biotechnological Equipment33 ( 1 ) 100 Просмотры
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Cytogenetic and Oxidative Status of Cultured Lymphocytes after Exposure to Extracts from Rhizopogon Mushrooms (Agaricomycetes) In Vitro

Ali ASLAN

In this study, acetone and water extracts obtained from edible mushrooms, Rhizopogon luteolus Fr. and Rh. roseolus (Corda) Th. Fr., containing important bioactive components were used. Total antioxidant capacity (TAC) and total oxidative stress (TOS) levels were examined on human peripheral lymphocyte culture treated with the respective extracts. Levels of genetic damage and cytotoxic effects of the respective extracts on lymphocytes were also tested. In general, when TAC levels of the extracts on cells were examined, a concentration-dependent increase was observed; a negative correlation was ...Более

Статья 2021 Fen Fakültesi International Journal of Medicinal Mushrooms23 ( 3 ) 100 Просмотры
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Prophylactic effect of myricetin and apigenin against lipopolysaccharide-induced acute liver injury

Ali ASLAN

Background Liver has an important role in the initiation and progression of multiple organ failure that occurs in sepsis. Many natural active substances can be used to reduce the liver injury caused by sepsis. For this aim, the effects of myricetin and apigenin on mice model of acute liver injury was evaluated in this study. Methods and results Thirty-six mice were randomly divided into six groups as; control, lipopolysaccharide (LPS) (5 mg/kg), LPS myricetin (100 mg/kg), LPS myricetin (200 mg/kg), LPS apigenin (100 mg/kg), and LPS apigenin (200 mg/kg) groups. Myricetin and apigenin were admin ...Более

Статья 2021 Fen Fakültesi Molecular Biology Reports48 ( 9 ) 47 Просмотры
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THE PHYSIOLOGICAL AND DNA DAMAGE RESPONSE OF IN THE LICHEN HYPOGYMNIA PHYSODES TO UV AND HEAVY METAL STRESS

Ali ASLAN

This work aims to determine the response of Hypogymnia physodes (L.) Nyl. (hooded tube lichen) collected in an unpolluted site (Yenice Forest in Karabiik, Turkey) to stress conditions. In the present study, the effect of exposure to different heavy metals (Cd 2, Pb 2, and Cr 6) for different durations and UV radiations dosages on lichen was examined at the physiological and molecular levels. The effects of stress conditions were determined in the case of different parameters concerning heavy metal, protein, chlorophyll, and carotenoid contents and changes in the DNA profiles. According to the ...Более

Статья 2020 Fen Fakültesi Applied Ecology and Environmental Research18 ( 2 ) 37 Просмотры
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