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Найденный: 38 Экземпляр 0.001 sn
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Synthesis of poly(Oak bark) particles from oak bark extract and its utilization as a drug carrier material

Nahit AKTAŞ

As oak bark extract includes pharmaceutically meaningful precious biochemicals such as vanillic acid, quercetin, catechin, caffeic acid, gallic acid, ferulic acid, syringic acid, chlorogenic acid, q-coumaric and protocatechuic acid, the present study focuses on synthesizing polymeric particles from that extract while keeping their targeted natural bioactivity. In this study, due to the bioavailability of oak bark extracts, poly(Oak bark)water extract (p(OB)w), poly(Oak bark)ethanol extract (p(OB)e) and poly(Oak bark)water-ethanol extract (p(OB)we) particles were synthesized using redox polymer ...Более

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Genetic analysis of PALB2 gene WD40 domain in canine mammary tumour patients

Ali RIŞVANLI

Background: DNA repair mechanisms are essential for tumorigenesis and disruption of HR mechanism is an important predisposing factor of human breast cancers (BC). PALB2 is an important part of the HR. There are similarities between canine mammary tumours (CMT) and BCs. As its human counterpart, PALB2 mutations could be a predisposing factor of CMT. Objectives: In this study, we aimed to investigate the impacts of PALB2 variants on tumorigenesis and canine mammary tumor (CMT) malignancy. Methods: We performed Sanger sequencing to detect germline mutations in the WD40 domain of the canine PALB2 ...Более

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Physiological and metabolic responses in Kök-Börü horses: Correlations with game outcomes

Ali RIŞVANLI | İsmail ŞEN | Kanat CANUZAKOV | Askarbek TÜLÖBAEV | Ruslan SALIKOV | Nezahat CEYLAN | Arina KAZAKBAYEVA | Ayday CUNUŞOVA | Nur ABDIMANAP UULU | Ünal TÜRKÇAPAR | Ulanbek ALİMOV

Background: The aim of this study was to examine variations in stress, metabolic, and physiological parameters of horses used in the traditional equestrian team sport of Kök-Börü in relation to winning and losing outcomes. Material and methods: To accomplish this, blood samples were taken from horses on four different teams who participated in two separate games, both before and after game. These samples were used to measure levels of cortisol, ACTH, beta-endorphin, adrenaline, noradrenaline, triiodothyronine (T3), and thyroxine (T4) via species-specific commercial ELISA kits. The autoanalyzer ...Более

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First record of tomato leafminer Tuta absoluta Meyrick (Lepidoptera: Gelechiidae) in Kyrgyzstan

Tair Esenalı Uulu

This short note reports the first record of the tomato leaf miner Tuta absoluta Meyrick (Lepidoptera: Gelechiidae) in Kyrgyzstan. This pest was found in February 2017 in greenhouses producing tomatoes, located 15 km from Bishkek. Identification of the pest was carried out in the Plant Protection Department, Çukurova University, Turkey based on the morphology of adults and larvae and the male genitalia. According to initial surveys this pest could be a major threat to tomato production in Kyrgyzstan.

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Fabrication of an Electrochemical E. coli Biosensor in Biowells Using Bimetallic Nanoparticle-Labelled Antibodies

Ali Osman SOLAK

An electrochemical biosensor was developed for the determination of Escherichia coli (E. coli) in water. For this purpose, silver-gold core-shell (Ag@Au) bioconjugates and anti-E. coli modified PS-microwells were designed in a sandwich-type format in order to obtain higher sensitivity and selectivity. Ag@Au bimetallic nanoparticles were synthesized by co-reduction method. The core-shell formation was analyzed by using UV-Vis spectroscopy and transmission electron microscopy. Biotin labeled anti-E. coli antibodies were coupled with Ag@Au nanoparticles to form bioconjugates. The electrochemical ...Более

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Evaluation of Some Redox Mediators in the Design of Reagentless Amperometric Glucose Biosensor

Ali Osman SOLAK

The influence of redox mediators (tetrathiafulvalene (TTF), tetrathiafulvalene-tetracyanoquinodimethane complex (TTF-TCNQ), phenazine methosulfate (PMS), 5,6-diamino-1,10-phenonthroline (5,6-DAP), potassium ferrocyanide (K4[Fe(CN)6]), methylene blue (MB) and toluidine blue (TB)) on the response of amperometric glucose biosensor was investigated in this research. Graphite rod electrode (GRE) modified by adsorbed mediator and glucose oxidase (GOx) cross-linked with glutaraldehyde was served as working electrode. The highest amperometric signals were observed by using TTF and TTF-TCNQ as mediator ...Более

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Synthesis, characterization, and application of silver nanoparticle-thiophenol nanocomposite film on the glassy carbon surface

Ali Osman SOLAK

In this study, 4-thiophenol modified glassy carbon electrode was prepared by the reduction of 4-diazothiophenol tetrafluoroborate salt. Silver nanoparticles were attached to the thiophenol modified surface to prepare a thiophenol-silver nanoparticle composite film. 4-Aminothiopenol molecules were deposited by self-assembling technique to form multi-layered nanofilms of TP/SNP/PhNH2 on glassy carbon substrate. These surfaces were characterized by cyclic voltammetry, electrochemical impedance spectroscopy, X-ray photoelectron spectroscopy, reflectance-absorption infrared spectroscopy, and ellips ...Более

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Biofuel Cell Based on Anode and Cathode Modified by Glucose Oxidase

Ali Osman SOLAK

A single compartment biofuel cell (BFC) based on an anode and a cathode powered by the same fuel glucose is reported. Glucose oxidase (GOx) from Aspergillus niger was applied as a glucose consuming biocatalyst for both anode and cathode of the BFC. The 5-amino-1,10-phenanthroline modified graphite rod electrode (GRE) with cross-linked GOx was used as the bioanode, and the GRE with co-immobilised horseradish peroxidase and GOx was exploited as the biocathode of the BFC. The open-circuit voltage of the designed BFC exceeded 450 mV and a maximal power density of 3.5 µW/cm2 was registered at a cel ...Более

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Detection of Escherichia coli O157:H7 using immunomagnetic separation and mPCR in Turkish foods of animal origin

Zafer GÖNÜLALAN

The present study was conducted to investigate the presence of Escherichia coli O157:H7 in food samples of animal origin and to detect its virulence genes by immunomagnetic separation technique and multiplex PCR (mPCR). A total of 500 samples (consisting of diced meat, minced meat, burger, raw cow's milk and raw cow's milk cheese) were analysed. Escherichia coli O157:H7 was detected in 5 (1%) of 500 analysed samples including two diced meat, one minced meat and two raw-milk cheese. None of the burger samples tested contained E. coli O157:H7. Three isolates obtained from minced and diced meat w ...Более

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Modification of glassy carbon electrode by the electrochemical oxidation of 3-aminophenylcalix[4]pyrrole in nonaqueous media

Ali Osman SOLAK

3-Aminophenylcalix[4]pyrrole (3APCP) was grafted to a glassy carbon (GC) surface during the electrochemical oxidation process in 0.1 M tetrabutylammoniumtetra-fluoroborate (TBATFB) containing acetonitrile solution. The presence of a surface film was confirmed electrochemically by comparing voltammograms of dopamine and ferricyanide redox probes at the bare and modified electrodes. Reflection-absorption infrared spectroscopy (RAIRS), XPS, atomic force microscopy (AFM), ellipsometry and the contact angle measurements were also employed to characterize 3APCP film on GC electrode. RAIRS analysis r ...Более

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Easy-to-Implement Ultra-Thin, Wide-Band, and Multi-Functional Polarization Converter for K and Ka Band Applications

Mehmet ERTUĞRUL

This article presents an ultrathin, broadband, and multipurpose polarization converter design utilizing an anisotropic metasurface for K and Ka band. The proposed polarization converter, which has a single layer F4B as a substrate material with hexagonal-shaped metallic solid structure along with hexagonal ring with diagonal splits on its front surface and a background (a completely metallic surface) on its back, works as not only a circular polarization converter but also a linear polarization to circular polarization (LP to CP) converter. Its polarization conversion rate (PCR) is more than 9 ...Более

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Carbon and oxygen stable isotopic evidence for diverse sheep and goat husbandry strategies amid a Final Bronze Age farming milieu in the Kyrgyz Tian Shan

Kubatbek TABALDİYEV

The mountains of Central Asia during the Bronze and Iron Ages are increasingly being reconceived as an important zone for intensive crop cultivation in combination with pastoralist herding. However, very little information is known about how farming practices intersected with livestock husbandry, especially at high-elevation sites. This paper presents the first insights to ancient animal management strategies in the Tian Shan through incremental carbon and oxygen stable isotope analysis of domesticated caprine teeth recovered from the Chap-1 farmstead located at 2000 m.a.s.l. in Kyrgyzstan (10 ...Более

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