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Найденный: 2 Экземпляр 0.000 sn
Базы данных : Taylor & Francis ✕Тематический рубрикатор : lichen ✕
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Potential human health risks of toxic/harmful elements by consumption of Pseudevernia furfuracea

Ali ASLAN

The potential human health risks of some toxic/harmful elements related to the consumption of Pseudevernia furfuracea (L.) Zopf. were investigated. The toxic/harmful elements (cadmium (Cd), chromium (Cr), copper (Cu), lead (Pb), manganese (Mn), nickel (Ni), and zinc (Zn)) were determined in P. furfuracea. According to the analysis result, the maximum (max.) toxic/harmful element value was 62 +/- 3.1 mg/kg for Mn and minimum (min.) value was 0.19 +/- 0.01 mg/kg for Cd. The estimated daily exposure doses (EDEXDs) for men, women and children were dietary (bread) > dietary (tea) > dermal. For diet ...Более

Статья 2021 Fen Fakültesi International Journal of Environmental Health Research32 ( 9 ) 44 Просмотры
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In vitro evaluation of cytotoxic, oxidative, genotoxic, and apoptotic activities of physodic acid from Pseudevernia furfuracea in HepG2 and THLE2 cells

Ali ASLAN

In the present study, cytotoxic (apoptotic and necrotic), antioxidant, prooxidant, genotoxic, and apoptosis-related genes expression modulatory effects of physodic acid (PA) isolated from Pseudevernia furfuracea on cancerous (HepG2) and healthy (THLE2) human liver cells were evaluated. Cytotoxic effects PA obtained from P. furfuracea on HepG2 and THLE2 cells were tested via MTT and LDH analyses. In order to determine genotoxic effect of PA, 8-OH-dG levels in the cells were measured. In addition, apoptotic or necrotic effects of PA on the hepatic cells were determined by qRT-PCR analysis. Cytot ...Более

Статья 2020 Fen Fakültesi Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology155 ( 6 ) 67 Просмотры
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