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Найденный: 2 Экземпляр 0.000 sn
Источник : Journal of Veterinar ... ✕Факультет / Институт : Veteriner Fakültesi ✕
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Effect of ketoprofen on intravenous pharmacokinetics of ganciclovir in chukar partridges (Alectoris chukar)

Ayday CUNUŞOVA

The aim of the study was to determine the effect of ketoprofen (2 mg/kg) on the intravenous pharmacokinetics of ganciclovir (10 mg/kg) in chukar partridges (Alectoris chukar). Eight clinically healthy partridges were used in the study. The study was performed in two periods using a cross-over design following a 15-day drug washout period. Plasma concentrations of ganciclovir were determined using the high-pressure liquid chromatography-ultraviolet detector and analyzed by non-compartmental analysis. The elimination half-life (t(1/2 lambda z)), area under the concentration-time curve (AUC(0-inf ...Более

Статья 2021 Veteriner Fakültesi Journal of Veterinary Pharmacology and Therapeutics45 ( 1 ) 82 Просмотры
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Pharmacokinetics and bioavailability of furosemide in sheep

Ayday CUNUŞOVA

The pharmacokinetics and bioavailability of furosemide were determined following intravenous (IV), intramuscular (IM), and subcutaneous (SC) administrations at 2.5 mg/kg dose in sheep. The study was conducted on six healthy sheep in a three-way, three-period, crossover pharmacokinetic design with a 15-day washout period. In first period, furosemide was randomly administered via IV to 2 sheep, IM to 2 sheep and SC to 2 sheep. In second and third periods, each sheep received furosemide via different routes of administration with the 15-day washout period. Plasma concentrations were determined us ...Более

Статья 2020 Veteriner Fakültesi Journal of Veterinary Pharmacology and Therapeutics44 ( 4 ) 62 Просмотры
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