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Background: Mastitis is a mammary gland inflammation that is very common worldwide, mostly caused by bacteria, and causes enormous economic losses. Many microorganisms cause this disease. The most common causes of mastitis by these microorganisms are Staphylococcus aureus (S. aureus), Escherichia coli (E. coli) and Streptococcus agalactiae (S. agalactiae). The anti-inflammatory properties of transforming growth factor (TGF)-beta include: 1) limiting interferon (IFN)-gamma production; 2) increasing the expression of the interleukine (IL)-1 receptor antagonist; 3) inhibiting macrophage productio ...Более