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Erişime Açık

Development of Urea Uptake and Release Studies Using N, N-Dimethylacrylamide/Maleic Acid/Citric Acid Based Macrogel

Nahit AKTAŞ

Recently, the use of polymers in agricultural and horticultural applications has been seen as a solution to reduce water consumption and excess fertilizer use in particularly. In this study, macrogels were synthesized to allow fertilizer species and water to be controlled and released in the soil. A natural macrogel derived from N,N-Dimethylacrylamide (DMAAm), Maleic Acid (MA) and Citric Acid (CA) was selected because of its ability to absorb/release a large amount of water and to have modifiable functional groups. Urea, which is an abundant source of nitrogen, was chosen to model the fertiliz ...Daha fazlası

Erişime Açık

Evaluation of poly(agar-co-glycerol-co-castor oil) organo-hydrogel as a controlled release system carrier support material

Nahit AKTAŞ

The aim of this study was to synthesize organo-hydrogels, by using agar, glycerol and different amounts of castor oil in one step, with biocompatible, blood-compatible and antioxidant properties using a new approach to the synthesis of smart polymers. Then, the target was to investigate the applicability of these organo-hydrogels as a drug release system. In the synthesis of organo-hydrogels, crosslinking was achieved with MBA or GA reagent and the redox polymerization technique was applied in the emulsion medium. The swelling behaviors of organo-hydrogels, which were synthesized using differe ...Daha fazlası

Erişime Açık

Application of Poly (Agar-Co-Glycerol-Co-Sweet Almond Oil) Based Organo-Hydrogels as a Drug Delivery Material

Nahit AKTAŞ

In this study, it was aimed to investigate the synthesis, characterization and drug release behaviors of organo-hydrogels containing pH-sensitive Agar (A), Glycerol (G), Sweet Almond oil (Wu et al. in J Mol Struct 882:107-115, 2008). Organo-hydrogels, which contained Agar, Glycerol and different amounts of Sweet Almond oil, were synthesized via the free-radical polymerization reaction with emulsion technique using glutaraldehyde or methylene bis acrylamide crosslinkers. Then, the degree of swelling, bond structures, blood compatibility and antioxidant properties of the synthesized organo-hydro ...Daha fazlası

Erişime Açık

Use of Coconut Oil-Based Organo-Hydrogels in Pharmaceutical Applications

Nahit AKTAŞ

In this study, six different organo-hydrogel containing Agar-Glycerol (AG) based Coconut Oil (CnO) were synthesized using different crosslinkers to ensure the controlled release of D-3 Vitamine and 5-Fluorouracil (5-Flu). Synthesized organo-hydrogels were characterized by FT-IR, Afterwards, swelling behaviors were investigated in ethanol, acetone, ethanol/ID water (1:1), acetone /ID water (1:1) and gasoline environments and different pH. As a result of hemolysis, blood clotting and antioxidant analysis, organo-hydrogels have been shown to have blood compatibility and antioxidant properties. Th ...Daha fazlası

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