Genetic analysis of PALB2 gene WD40 domain in canine mammary tumour patients

Ali RIŞVANLI

Background: DNA repair mechanisms are essential for tumorigenesis and disruption of HR mechanism is an important predisposing factor of human breast cancers (BC). PALB2 is an important part of the HR. There are similarities between canine mammary tumours (CMT) and BCs. As its human counterpart, PALB2 mutations could be a predisposing factor of CMT. Objectives: In this study, we aimed to investigate the impacts of PALB2 variants on tumorigenesis and canine mammary tumor (CMT) malignancy. Methods: We performed Sanger sequencing to detect germline mutations in the WD40 domain of the canine PALB2 ...Daha fazlası

Makale 2024 Veteriner Fakültesi Veterinary Medicine and Science10 ( 3 ) 32 Görüntülenme

Physiological and metabolic responses in Kök-Börü horses: Correlations with game outcomes

Ali RIŞVANLI | İsmail ŞEN | Kanat CANUZAKOV | Askarbek TÜLÖBAEV | Ruslan SALIKOV | Nezahat CEYLAN | Arina KAZAKBAYEVA | Ayday CUNUŞOVA | Nur ABDIMANAP UULU | Ünal TÜRKÇAPAR | Ulanbek ALİMOV

Background: The aim of this study was to examine variations in stress, metabolic, and physiological parameters of horses used in the traditional equestrian team sport of Kök-Börü in relation to winning and losing outcomes. Material and methods: To accomplish this, blood samples were taken from horses on four different teams who participated in two separate games, both before and after game. These samples were used to measure levels of cortisol, ACTH, beta-endorphin, adrenaline, noradrenaline, triiodothyronine (T3), and thyroxine (T4) via species-specific commercial ELISA kits. The autoanalyzer ...Daha fazlası

Makale 2024 Veteriner Fakültesi Veterinary Medicine and Science10 ( 3 ) 0 Görüntülenme

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Genetic analysis of PALB2 gene WD40 domain in canine mammary tumour patients

Ali RIŞVANLI

Physiological and metabolic responses in Kök-Börü horses: Correlations with game outcomes

Ali RIŞVANLI | İsmail ŞEN | Kanat CANUZAKOV | Askarbek TÜLÖBAEV | Ruslan SALIKOV | Nezahat CEYLAN | Arina KAZAKBAYEVA | Ayday CUNUŞOVA | Nur ABDIMANAP UULU | Ünal TÜRKÇAPAR | Ulanbek ALİMOV