Hepatic stellate cells increase in Toxoplasma gondii infection in mice

Oğuz KUL

Background: Toxoplasma gondii is a ubiquitous protozoan parasite that can infect humans and animals. The severity of toxoplasmosis varies according to the immune status of the individual, parasite strain, and host species. In mammalian species, it has been observed that severe lesions of acute toxoplasmosis form in visceral organs such as the liver, lung, and spleen. Some epidemiological studies have reported an association of T. gondii infection with liver cirrhosis. Methods. Acute infection was induced in fifteen 30-day-old normal Swiss albino mice. The mice were infected by intraperitoneal ...Daha fazlası